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98-92-0 - Nicotinamide, 99% - Niacinamide - Pyridine-3-carboxamide - A15970 - Alfa Aesar

A15970 Nicotinamide, 99%

CAS 번호
98-92-0
동의어
Niacinamide
Pyridine-3-carboxamide

사이즈 가격 ($) 수량 재고 여부
100g 17.00
250g 25.90
1000g 79.70
장바구니에 추가 대량 견적에 추가 항목 보기

Nicotinamide, 99%

MDL
MFCD00006395
EINECS
202-713-4

화학적 특성

화학식
C6H6N2O
화학 식량
122.13
융점
128-132°
인화점
182°(360°F)
밀도
1.40
용해도
Soluble in water, ethanol , glycerol, DMSO , methanol, butanol and chloroform. Slightly soluble in ether.

용도

Nicotinamide is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). It may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule. It is an amide derivative of vitamin B3 and a PARP inhibitor.

참고

Stable under recommended storage conditions. Incompatible with oxidizing agents.

참조 문헌

Kevin J.Bitterman; Rozalyn M.Anderson; Haim Y.Cohen; Magda Latorre-Esteves; David A.Sinclair. Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of Yeast Sir2 and Human SIRT1. The Journal of Biological Chemistry. 2002, 277, (47),45099-45107

 

Rozalyn M.Anderson; Kevin J.Bitterman; Jason G.Wood; Oliver Medvedik; David A.Sinclair. Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae. Letters to Nature. 2003, 423, 181-185

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H319

Causes serious eye irritation.

주의 설명서: P280i-P264-P305+P351+P338-P337+P313

Wear eye/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention.

기타 참조

Merck
14,6523
바일슈타인
383619
통합 관세 코드
2936.29
TSCA(독성물질규제법)"
Yes
RTECS(화학물질 독성 등록)
QS3675000

권장

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