2-Bromo-5-(trifluoromethyl)aniline is used in the synthesis and biochemical evaluation of series of inhibitors of hepatitis C virus (HCV) NS3 protease.
Robert Rönn.; Anna Lampa.; Shane D. Peterson.; Thomas Gossas.; Eva Åkerblom.; U. Helena Danielson.; Anders Karlén.; Anja Sandström. Hepatitis C virus NS3 protease inhibitors comprising a novel aromatic P1moiety.Bioorg Med Chem.,
Tomoki Takeuchi.; Shinya Oishi.; Toshiaki Watanabe.; Hiroaki Ohno.; Jun-ichi Sawada.; Kenji Matsuno.; Akira Asai.; Naoya Asada.; Kazuo Kitaura.; and Nobutaka Fujii. Structure-Activity Relationships of Carboline and Carbazole Derivatives as a Novel Class of ATP-Competitive Kinesin Spindle Protein Inhibitors.J. Med. Chem.,2011,54(13), 4839-4846.
해저드 설명서 (EU): H302-H311-H332-H315-H319
Harmful if swallowed. Toxic in contact with skin. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation.
주의 설명서: P280h-P305+P351+P338-P309-P310a-P302+P352a
Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Immediately call a POISON CENTER/doctor IF ON SKIN: Wash with plenty of water.