L-Glutathione is used in the treatment of lung diseases for patients who are HIV positive. It protects the cancerous cells by conferring resistance to chemotherapeutic drugs. It is involved in many aspects of metabolism including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds. As an antioxidant, it prevents damage to important cellular components that arise due to reactive oxygen species like free radicals and peroxide. It is also used to decrease the concentrations of inflammatory cytokines (IL-6, IL-18) as well as involved in increasing the level of serum Ca2+ ions. It is also used in white wine production.
Calborean, A.; Martin, F.; Marconi, D.; Turcu, R.; Kacso, I. E.; Iarinca, L. B.; Graur, F.; Turcu, I. Adsorption mechanisms of l-Glutathione on Au and controlled nano-patterning through Dip Pen Nanolithography. Mater. Sci. Eng., C 2015, 57, 171-180.
Wang, X.; Chen, X.; Evans, D. G.; Yang, W. A novel biosensor for reduced l-glutathione based on cobalt phthalocyaninetetrasulfonate-intercalated layered double hydroxide modified glassy carbon electrodes. Sens. Actuators, B 2011, 160 (1), 1444-1449.