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4-Methyl-1H-pyrazole is used as an antidote in methanol and ethylene glycol poisoning. It is also employed as an alcohol dehydrogenase inhibitor. It acts a ligand in coordination chemistry. Further, it serves as an intermediate in organic synthesis.
Vlaicu, I. D.; Olar, R.; Marinescu, D.; Lazar, V.; Badea, M. Physico-chemical and thermal characterisation of new Co(II) complexes with pyrazole derivatives. J. Therm. Anal. Calorim. 2013, 113 (3), 1337-1343.
Boji?, M.; Sedgeman, C. A.; Nagy, L. D.; Guengerich, F. P. Aromatic hydroxylation of salicylic acid and aspirin by human cytochromes P450. Eur. J. Pharm. Sci. 2015, 73, 49-56.
Finnerty, N.; O'Riordan, S. L.; Klamer, D.; Lowry, J.; Pålsson, E. Increased brain nitric oxide levels following ethanol administration. Nitric Oxide 2015, 47, 52-57.
해저드 설명서 (EU): H302-H315-H319-H335
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
주의 설명서: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.