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90719-32-7 - (S)-(-)-4-Benzyl-2-oxazolidinone, 99% - A18236 - Alfa Aesar

A18236 (S)-(-)-4-Benzyl-2-oxazolidinone, 99%

CAS 번호
90719-32-7
동의어

사이즈 가격 ($) 수량 재고 여부
1g 29.50
5g 96.60
25g 292.00
장바구니에 추가 대량 견적에 추가 항목 보기

(S)-(-)-4-Benzyl-2-oxazolidinone, 99%

MDL
MFCD00064496

화학적 특성

화학식
C10H11NO2
화학 식량
177.20
융점
87-89°
감도
Hygroscopic
용해도
Insoluble in water.

용도

(S)-(-)-4-Benzyl-2-oxazolidinone is used in chiral auxiliary asymmetric alkylation. It has been used in the synthesis of (S)-equol. Preparation and functionalization of chiral, stabilized ylides. It was used for asymmetric synthesis of (3R)- and (3S)-piperazic acid.

참고

Hygroscopic. Incompatible with oxidizing agents.

참조 문헌

David J.Madar; Hana Kopecka; Daisy Pireh; Jonathan Pease; Marina Pliushchev; Richard J.Sciotti; Paul E.Wiedeman; Stevan W.Djuric. Synthesis of N-arylated oxazolidinones via a palladium catalyzed cross coupling reaction. Application to the synthesis of the antibacterial agent Dup-721. Tetrahedron Letters. 2001, 42,(22), 3681-3684.

 

Ralf-Siegbert Hauck; Heinz Nau. The enantiomers of the valproic acid analogue 2-n-propyl-4-pentynoic acid (4-yn-VPA): Asymmetric synthesis and highly stereoselective teratogenicity in mice. Pharmaceutical Research. 1992, 9,(7), 850-855.

Evans chiral auxiliary; compare (4S)-(-)-Isopropyl-2-oxazolidinone, A14029.

For details of use in enantioselective aldol condensation, see: Org. Synth. Coll., 8, 339 (1993):

A simplified method of acylation of the oxazolidinone, avoiding the need for rigorously anhydrous conditions, has been reported using acyl chlorides, anhydrides or pivaloyl mixed anhydrides as the acylating agents catalyzed by DMAP: Synthesis, 1283 (1996).

See also (4S)-(-)-Isopropyl-2-oxazolidinone, A14029.

기타 참조

바일슈타인
3649667
통합 관세 코드
2934.99
TSCA(독성물질규제법)"
No

권장

  • A10162

    tert-Butylacetyl chloride, 98+%
  • A11822

    Allyl iodide, 97+%, stab. with copper
  • A15000

    Ammonium chloride, 98+%
  • A16770

    (R)-(+)-4-Benzyl-2-oxazolidinone, 99%
  • L08779

    Sodium bis(trimethylsilyl)amide, 1M soln. in THF

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화학물질

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