1-Bromo-2-methoxy-naphthalene is a useful synthetic intermediate. It is used as a reagent to synthesize a catalyst for highly enantioselective aziridination of styrene derivatives. It can also be used to prepare biaryls or biheterocycles by palladium-catalyzed Ullmann coupling.
M. Carmen Carreno; Jose L. Garcia Ruano; Gema Sanz; Miguel A. Toledo; Antonio Urbano. N-Bromosuccinimide in Acetonitrile: A Mild and Regiospecific Nuclear Brominating Reagent for Methoxybenzenes and Naphthalenes. J. Org. Chem., 1995, 60 (16), 5328-5331.
George Majetich; Rodgers Hicks; and Steven Reister. Electrophilic Aromatic Bromination Using Bromodimethylsulfonium Bromide Generated in Situ. J. Org. Chem, 1997, 62(13), 4321-4326.