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57-66-9 - Probenecid, 98% - 4-(Di-n-propylaminosulfonyl)benzoic acid - 4-(Di-n-propylsulfamoyl)benzoic acid - B20010 - Alfa Aesar

B20010 Probenecid, 98%

CAS 번호
57-66-9
동의어
4-(Di-n-propylaminosulfonyl)benzoic acid
4-(Di-n-propylsulfamoyl)benzoic acid

사이즈 가격 ($) 수량 재고 여부
2.5g 49.30
10g 148.00
장바구니에 추가 대량 견적에 추가 항목 보기

Probenecid, 98%

MDL
MFCD00038402
EINECS
200-344-3

화학적 특성

화학식
C13H19NO4S
화학 식량
285.36
융점
198-199°
용해도
Soluble in water (partly miscible), solutions of alkali hydroxides,, ethanol (100 mM), acetone, chloroform, sodium hydroxide (1 M), DMSO (100 mM), methanol, dilute acids (practically insoluble), dilute alkalies, and ether (slightly soluble).

용도

It is a uricosuric drug, that is, it increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia. Probenecid was developed as an alternative to caronamide to competitively inhibit renal excretion of some drugs, thereby increasing their plasma concentration and prolonging their effects.

참고

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

참조 문헌

Campos-Arroyo D, et al. Probenecid is a chemosensitizer in cancer cell lines.Cancer chemotherapy and pharmacology.1992,69(2), 495-504.

Robbins N, et al. The history and future of probenecid.Cardiovascular toxicology.2012,12(1), 1-9.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H301-H315-H319-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

주의 설명서: P261-P280a-P301+P310a-P305+P351+P338-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

Merck
14,7754
통합 관세 코드
2935.90
TSCA(독성물질규제법)"
Yes
RTECS(화학물질 독성 등록)
DG9400000

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