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56-75-7 - (R,R)-Chloramphenicol, 99+% - Chloromycetin - B20841 - Alfa Aesar

B20841 (R,R)-Chloramphenicol, 99+%

CAS 번호
56-75-7
동의어
Chloromycetin

사이즈 가격 ($) 수량 재고 여부
25g 46.40
100g 137.00
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(R,R)-Chloramphenicol, 99+%

MDL
MFCD00078159
EINECS
200-287-4

화학적 특성

화학식
C11H12Cl2N2O5
화학 식량
323.14
융점
149-152°
용해도
Soluble in alcohol, propylene, glycol, acetone and ethyl acetate. Slightly soluble in water.

용도

Inhibitor of translation on the 50S subunit at the peptidyltransferase step. (R,R)-Chloramphenicol is widely utilized as an antibiotic, which is used for the treatment of number of bacterial infections and also act as a bacteriostatic. It is often used for bacterial selection in molecular biology applications. It also finds an application in ophthalmic and veterinary purposes. It also protects the mitochondrial and chloroplast protein synthesis and ribosomal formation of (p)ppGpp, de-pressing rRNA transcription.

참고

Keep the container tightly sealed. Incompatible with strong oxidizing agents.

참조 문헌

Fedeniuk, R. W.; Mizuno, M.; Neiser, C.; O’Byrne, C. Development of LC-MS/MS methodology for the detection/determination and confirmation of chloramphenicol, chloramphenicol 3-O- β-d-glucuronide, florfenicol, florfenicol amine and thiamphenicol residues in bovine, equine and porcine liver. J. Chromatogr. B 2015, 991, 68-78.

Mitchell, S. M.; Ullman, J. L.; Teel, A. L.; Watts, R. J. Hydrolysis of amphenicol and macrolide antibiotics: Chloramphenicol, florfenicol, spiramycin, and tylosin. Chemosphere 2015, 134, 504-511.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H303-H350-H361

May be harmful if swallowed. May cause cancer. Suspected of damaging fertility or the unborn child.

주의 설명서: P201-P280-P312a-P308+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. Call a POISON CENTER/doctor if you feel unwell. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

Merck
14,2077
바일슈타인
2225532
통합 관세 코드
2941.40
TSCA(독성물질규제법)"
Yes
RTECS(화학물질 독성 등록)
AB6825000

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