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Diethyl hydroxymethylphosphonate acts as a reactant for synthesis of α And β-dialkoxyphosphoryl isothiocyanate used in antiproliferative studies, dendritic polyglycerol anions for L-selectin inhibition, phosphonates for anti-HIV-1 activity, homo and copolymers of phosphonated norbornenes, Mitsunobu reactions. It is involved in studies of FBPase inhibition by phosphonic acid-containing thaizoles.
Mateusz Psurski; Katarzyna Błażewska; Anna Gajda; Tadeusz Gajda; Joanna Wietrzyk; Józef Oleksyszyn. Synthesis and antiproliferative activity of novel α- and β-dialkoxyphosphoryl isothiocyanates. Bioorganic & Medicinal Chemistry Letters.2011, 21 (15), 4572-4576.
Marie Weinhart; Dominic Gröger; Sven Enders; Jens Dernedde; Rainer Haag. Synthesis of dendritic polyglycerol anions and their efficiency toward L-selectin inhibition. Biomacromolecules.2011, 12 (7), 2502-2511.
해저드 설명서 (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
주의 설명서: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.