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154-42-7 - 6-Thioguanine, 98% - 2-Amino-6-mercaptopurine - 2-Amino-6-purinethiol - B21280 - Alfa Aesar

B21280 6-Thioguanine, 98%

CAS 번호
154-42-7
동의어
2-Amino-6-mercaptopurine
2-Amino-6-purinethiol

사이즈 가격 ($) 수량 재고 여부
1g 62.00
5g 257.00
장바구니에 추가 대량 견적에 추가 항목 보기

6-Thioguanine, 98%

MDL
MFCD00233553
EINECS
205-827-2

화학적 특성

화학식
C5H5N5S
화학 식량
167.19
융점
>360°
용해도
Soluble in dilute solutions of alkali hydroxides and hot alcohol. Insoluble in water.

용도

6-Thioguanine acts as an antineoplastic and purine antimetabolite. It is also useful as an inhibition of stimulated expression of TNF-related apoptosis-inducing ligand (TRAIL) protein. It is involved in the treatment of acute leukemias and Psoriasis. Further, it is used for the treatment of ulcerative colitis and autoimmune diseases.

참고

Incompatible with strong oxidizing agents.

참조 문헌

LaDuke, K. E.; Ehling, S.; Cullen, J. M.; Bäumer, W.; Habil, M. V. Effects of azathioprine, 6-mercaptopurine, and 6-thioguanine on canine primary hepatocytes. Am. J. Vet. Res. 2015, 76 (7), 649-655.

Li, P.; Gu, H.; Zhang, J. Characterization of the Interaction of 6-Thioguanine with Human Serum Albumin by Surface-Enhanced Raman Scattering and Molecular Modeling. Anal. Lett. 2015, 48 (13), 2063-2074.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H301

Toxic if swallowed.

주의 설명서: P264-P270-P301+P310a-P321-P405-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Immediately call a POISON CENTER/doctor Specific treatment (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

Merck
14,9337
바일슈타인
157765
위험 등급
6.1
포장 그룹
III
통합 관세 코드
2933.59
TSCA(독성물질규제법)"
No
RTECS(화학물질 독성 등록)
UP0740000

권장

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  • A11543

    Methacrylic acid, 99%, stab. with 100-250ppm hydroquinone or 4-methoxyphenol
  • A12197

    6-Mercaptopurine monohydrate, 98%
  • B20303

    1,8,9-Trihydroxyanthracene, 97%
  • B24079

    Nitrofurantoin, 98%

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