Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

220141-70-8 - 5-Fluoroorotic acid monohydrate, 98% - 5-Fluorouracil-6-carboxylic acid monohydrate - B21290 - Alfa Aesar

B21290 5-Fluoroorotic acid monohydrate, 98%

CAS 번호
220141-70-8
동의어
5-Fluorouracil-6-carboxylic acid monohydrate

사이즈 가격 ($) 수량 재고 여부
50mg 33.30
250mg 113.00
1g 280.00
장바구니에 추가 대량 견적에 추가 항목 보기

5-Fluoroorotic acid monohydrate, 98%

MDL
MFCD00150658
EINECS
211-876-0

화학적 특성

화학식
C5H3FN2O4•H2O
화학 식량
192.11 (174.09anhy)
융점
ca 255° dec.
용해도
Soluble in water, dimethyl sulfoxide, 50mg in 1ml (1:1 ammonium hydroxide: water) with gentle heating.

용도

5-Fluoroorotic Acid, Monohydrate (5-FOA) has become a valuable tool for research in the field of molecular genetics and has been employed in the selection of resistant strains of Saccharomyces cerevisiae that possess a mutant URA3 gene which renders them orotidine-5í-phosphate decarboxylation.

참고

Store in freezer (-20°C). Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

참조 문헌

W. M. Macintyre; and M. Zirakzadeh. The crystal and molecular structure of the monohydrate of the rubidium salt of 5-fluoroorotic acid. Acta Cryst., 1964, 171305-1311.

V. H. Bono Jr.; C. C. Cheng; E. Frei III; and M. G. Kelly. Methyl-5-fluoroorotate: Synthesis and Comparison with 5-Fluoroorotic Acid with Respect to Biological Activity and Cell Entry. Cancer Res., 1964, 24513.

Reagent used in the selection of mutant URA3 gene strains of Saccharomyces Cerevisiae: Genetics, 107, 179 (1984); Methods Enzymol., 154, 164 (1987).

Potential antimalarial agent: Antimicrob. Agents Chemother., 40, 914 (1996).

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

주의 설명서: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

Merck
14,4176
바일슈타인
181933
통합 관세 코드
2933.59
TSCA(독성물질규제법)"
No
RTECS(화학물질 독성 등록)
UV7800000

권장

최근에 본 것

화학물질

화학물질

금속 및 재료

촉매

분석 기기 및 실험실 용품