I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
1-Methylpyrrole, can be used as organic synthetic materials, widely used in medicine. It is also used as a pharmaceutical intermediate.
TT Dang.; R Ahmad.; TT Dang.; H Reinke.; P Langer. Regioselective Suzuki cross-coupling reactions of 2, 3, 4, 5-tetrabromo-1-methylpyrrole. Tetrahedron Letters. 200849 (10), 1698-1700.
JR Carson.; DN McKinstry.; S Wong. 5-Benzoyl-1-methylpyrrole-2-acetic acids as antiinflammatory agents. J. Med. Chem. 197114 (7), 646-647.
Lithiation occurs at the 2-position. Excess n-BuLi in the presence of TMEDA leads to 2,5-dimetallation: J. Chem. Soc. Perkin I, 887 (1977).
Reaction of benzenoid aromatics with lactones under Friedel-Crafts conditions normally results in alkylation. With 1-methylpyrrole and - or δ-lactones in the presence of AlCl3, acylation at the 2-position predominates: Tetrahedron Lett., 36, 6739 (1995).
해저드 설명서 (EU): H225-H302-H315-H335
Highly flammable liquid and vapour. Harmful if swallowed. Causes skin irritation. May cause respiratory irritation.
주의 설명서: P210-P261-P280a-P303+P361+P353-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.