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64-77-7 - Tolbutamide, 98% - 1-n-Butyl-3-(p-tolylsulfonyl)urea - B21698 - Alfa Aesar

B21698 Tolbutamide, 98%

CAS 번호
64-77-7
동의어
1-n-Butyl-3-(p-tolylsulfonyl)urea

사이즈 가격 ($) 수량 재고 여부
10g 45.90
50g 153.00
250g 543.00
장바구니에 추가 대량 견적에 추가 항목 보기

Tolbutamide, 98%

MDL
MFCD00027169
EINECS
200-594-3

화학적 특성

화학식
C12H18N2O3S
화학 식량
270.35
융점
128-130°
용해도
Soluble in chloroform.

용도

Tolbutamide, have been used in a cDNA microarray assay to probe changes in gene expression in HepG2 cells upon their administration. It has been utilized to counteract insulin activity in a patch-clamp investigation of ATP sensitive K+ channels in mouse pancreatic β-cells. The activity of various biotransformation enzymes in cultured primary rat proximal tubular cells in the presence of tolbutamide and other compounds has been studied.

참고

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

참조 문헌

Sullivan-Klose,et.al. The role of the CFP2C9-Leu 359 allelic variant in the tolbutamide polymorphism. Pharmacogenetics. 1996, 6 (4), 2702-2705.

Michael Perley, MD; and David M Kipnis, MD. Plasma Insulin Responses to Glucose and Tolbutamide of Normal Weight and Obese Diabetic and Nondiabetic Subjects. Diabetes, 1966, 15(12), 867-874.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H302-H317

Harmful if swallowed. May cause an allergic skin reaction.

주의 설명서: P261-P280g-P301+P312a-P363-P321-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Wash contaminated clothing before reuse. Specific treatment (see label). Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

Merck
14,9507
바일슈타인
1984428
통합 관세 코드
2935.90
TSCA(독성물질규제법)"
Yes
RTECS(화학물질 독성 등록)
YS4550000

권장

  • J60426

    Quinidine sulfate dihydrate, 98+%

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