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178312-62-4 - Homomorpholine hydrochloride, 98% - Hexahydro-1,4-oxazepine hydrochloride - 1,4-Oxazepane hydrochloride - B21749 - Alfa Aesar

B21749 Homomorpholine hydrochloride, 98%

CAS 번호
178312-62-4
동의어
Hexahydro-1,4-oxazepine hydrochloride
1,4-Oxazepane hydrochloride

사이즈 가격 ($) 수량 재고 여부
1g 249.00
5g 909.00
장바구니에 추가 대량 견적에 추가 항목 보기

Homomorpholine hydrochloride, 98%

MDL
MFCD02683070

화학적 특성

화학식
C5H11NO•HCl
화학 식량
137.61
융점
158-164°
감도
Hygroscopic
용해도
Slightly soluble in water.

용도

Homomorpholine Hydrochloride is a useful synthetic intermediate. It is used to prepare homomorpholine oxazolidinone with antibacterial activities. It is also used to synthesize A2A adenosine receptor antagonists for the treatment of Parkinson's disease.

참고

Hygroscopic. Keep away from oxidizing agents, water/moisture. Store under inert atmosphere. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

참조 문헌

Ji-Young Kim; Frederick E. Boyer; Allison L. Choy; Michael D. Huband; Paul J. Pagano; J.V.N. Vara Prasad. Synthesis and structure-activity studies of novel homomorpholine oxazolidinone antibacterial agents.Bioorganic & Medicinal Chemistry Letters.200919(2), 550-553.

Zhang, X., et al. Lead Optimization of 4-Acetylamino-2-(3,5-dimethylpyrazol-1-yl)-6-pyridylpyrimidines as A2A Adenosine Receptor Antagonists for the Treatment of Parkinson’s Disease.J. Med. Chem.200851(22), 7099-7110.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

주의 설명서: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

통합 관세 코드
2934.99
TSCA(독성물질규제법)"
No

권장

  • B24073

    3-Chloro-alpha-toluenesulfonyl chloride, 96%
  • L19637

    Isoquinoline-5-carboxylic acid, 96%

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