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27489-62-9 - trans-4-Aminocyclohexanol, 98+% - trans-4-Hydroxycyclohexylamine - B22365 - Alfa Aesar

B22365 trans-4-Aminocyclohexanol, 98+%

CAS 번호
27489-62-9
동의어
trans-4-Hydroxycyclohexylamine

사이즈 가격 ($) 수량 재고 여부
5g 38.20
25g 129.00
100g 386.00
장바구니에 추가 대량 견적에 추가 항목 보기

trans-4-Aminocyclohexanol, 98+%

MDL
MFCD00067698
EINECS
248-492-8

화학적 특성

화학식
C6H13NO
화학 식량
115.18
융점
110-113°
감도
Air Sensitive
용해도
Soluble in water.

용도

trans-4-Aminocyclohexanol is used as raw material in organic synthesis and is an important intermediate in the synthesis of drugs such as Ambroxol hydrochloride. It can react with butyric acid-(2-chloro-ethyl ester) to get butyric acid 4-amino-cyclohexyl ester. This reaction needs catalytic agent Aspergillus niger lipase and solvent 2-methyl-butan-2-ol.

참고

Air Sensitive. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

참조 문헌

Thomas P. Johnston.; George S. McCaleb.; John A. Montgomery. Synthesis and biologic evaluation of major metabolites of N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea. J. Med. Chem. 1975, 18, (6), 634-637.

Jie Cheng.; Mark L. Trudell. Synthesis of N-Heteroaryl-7-azabicyclo[2.2.1]heptane Derivatives via Palladium-Bisimidazol-2-ylidene Complex Catalyzed Amination Reactions. Org. Lett.2001, 3, (9), 1371-1374.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

주의 설명서: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a

Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

위험 등급
8
포장 그룹
III
통합 관세 코드
2922.19
TSCA(독성물질규제법)"
No

권장

최근에 본 것

화학물질

화학물질

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