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1538-75-6 - Trimethylacetic anhydride, 99% - Pivalic anhydride - B22983 - Alfa Aesar

B22983 Trimethylacetic anhydride, 99%

CAS 번호
1538-75-6
동의어
Pivalic anhydride

사이즈 가격 ($) 수량 재고 여부
25g 45.00
100g 130.00
500g 593.00
장바구니에 추가 대량 견적에 추가 항목 보기

Trimethylacetic anhydride, 99%

MDL
MFCD00008842
EINECS
216-263-1

화학적 특성

화학식
C10H18O3
화학 식량
186.25
비등점
193°
인화점
63°(145°F)
밀도
0.918
굴절률
1.4090
감도
Moisture Sensitive
용해도
Miscible with acetonitrile.

용도

Trimethylacetic anhydride is used as acylation and esterification reagents. It is involved in acylation and esterification reactions with anilines and phenols. It is also used in solid-phase oligonucleotide synthesis and in the kinetic resolution of racemic 2-hydroxy-gamma-butyrolactones with diphenylacetic acid. It is also employed in the production of cyano-4, N-tert-butyloxycarbonyl piperidine.

참고

Moisture sensitive. Incompatible with strong oxidizing agents, strong acids, strong bases and strong reducing agents.

참조 문헌

The direct hydrogenation of carboxylic acids to aldehydes has been achieved in the presence of pivalic anhydride and Tetrakis(triphenyl­phosphine)­palladium(0)­, 10548 : Chem. Lett., 1143 (1998).

Alcohols can be protected as their pivaloyl (Pv) esters by reaction with the anhydride in the presence of MgBr2 - Et3N or Sc(OTf)3 in acetonitrile: J. Org. Chem., 61, 5702 (1996). See also Trimethyl­acetyl­ chloride, A15051 .

Zhu, J. L.; Liu, Y.; Liu, X. Y.; Liu, H. J.; Chen, Y. Multi stimuli-responsive photoluminescent nanocomposite of silver nanoclusters with hyperbranched polyethylenimine derivatives. RSC Adv. 2015, 5 (11), 8146-8151.

Wu, J.; Leng, W. L.; Liao, H.; Hoang, K. L. M.; Le, K.; Liu, X. W. Intramolecular C-N Bond Formation under Metal-free Conditions: Synthesis of Indolizines. Chem. Asian J. 2015, 10 (4), 853-856.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H227-H314-H318

Combustible liquid. Causes severe skin burns and eye damage. Causes serious eye damage.

주의 설명서: P280-P305+P351+P338-P309-P310a

Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Immediately call a POISON CENTER/doctor

기타 참조

바일슈타인
386552
위험 등급
8
포장 그룹
III
통합 관세 코드
2915.90
TSCA(독성물질규제법)"
Yes

권장

  • A11766

    Allyl bromide, 99%, stab. with 300-1000ppm Propylene oxide
  • A12245

    Succinic anhydride, 99%
  • A13064

    tert-Butyldimethylchlorosilane, 97%
  • A13614

    Trifluoroacetic anhydride, 99+%
  • B23003

    1,2,4-Benzenetricarboxylic anhydride, 97%

최근에 본 것

화학물질

화학물질

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