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612-62-4 - 2-Chloroquinoline, 99% - B23443 - Alfa Aesar

B23443 2-Chloroquinoline, 99%

CAS 번호
612-62-4
동의어

사이즈 가격 ($) 수량 재고 여부
5g 87.50
25g 252.00
장바구니에 추가 대량 견적에 추가 항목 보기

2-Chloroquinoline, 99%

MDL
MFCD00006741
EINECS
210-317-8

화학적 특성

화학식
C9H6ClN
화학 식량
163.61
융점
34-37°
비등점
265-267°
인화점
>110°(230°F)
밀도
1.230
용해도
Soluble in ethanol, ether, methanol, and chloroform. Insoluble in water.

용도

2-Chloroquinoline is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. It reacts with benzotriazole, followed by cyclization with loss of nitrogen, gives the indolo[2,3-b]quinoline ring system for use in novel cytotoxic DNA topoisomerase II inhibitors.

참고

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible materials are oxidizing agents. Store at room temperature.

참조 문헌

Faisal Hayat; Emma Moseley; Attar Salahuddin; Robyn L Van Zyl; Amir Azam. Antiprotozoal activity of chloroquinoline based chalcones. European Journal of Medicinal Chemistry.2011, 46, (5), 1897-1905.

Mohammed Salem Al-Dosari; Mostafa Mohamed Ghorab; Mansour Sulaiman Al-Said; Yassin Mohammed Nissan. Discovering some novel 7-chloroquinolines carrying a biologically active benzenesulfonamide moiety as a new class of anticancer agents. Chemical & Pharmaceutical Bulletin.2013, 61, (1), 50-58.

Reaction with benzotriazole, followed by cyclization with loss of nitrogen, gives the indolo[2,3-b]quinoline ring system for use in novel cytotoxic DNA topoisomerase II inhibitors: J. Med. Chem., 37, 3503 (1994):

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

주의 설명서: P280g-P305+P351+P338-P337+P313

Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention.

기타 참조

바일슈타인
112561
통합 관세 코드
2933.49
TSCA(독성물질규제법)"
Yes
RTECS(화학물질 독성 등록)
VB2320000

권장

최근에 본 것

화학물질

화학물질

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