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67-20-9 - Nitrofurantoin, 98% - N-(5-Nitro-2-furfurylidene)-1-aminohydantoin - B24079 - Alfa Aesar

B24079 Nitrofurantoin, 98%

CAS 번호
67-20-9
동의어
N-(5-Nitro-2-furfurylidene)-1-aminohydantoin

사이즈 가격 ($) 수량 재고 여부
25g 42.10
100g 120.00
500g 481.00
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Nitrofurantoin, 98%

MDL
MFCD00003224
EINECS
200-646-5

화학적 특성

화학식
C8H6N4O5
화학 식량
238.16
융점
ca 265° dec.
감도
Light Sensitive & Hygroscopic
용해도
Soluble in water (<0.01 g/100 ml at 19°C), dimethyl sulfoxide and methanol.

용도

Nitrofurantoin is a nitrofuran antibiotic that is used as a substrate of bacterial nitrofuran reductase to study the interactions of active metabolites with DNA, ribosomal proteins and metabolic and pro-oxidant processes. It is an antibactericidal compound that has been historically prepared by the reaction of 1-aminohydantoin sulfate and 5-nitro-2-furaldehyde diacetate. It shows activity against many Gram-positive and Gram-negative bacteria. Nitrofurantoin is effective against enterococci, staphylococci, streptococci, corneybacteria, many strains of Escherichia coli.

참고

Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Store under dry inert gas. It is hygroscopic in nature. Incompatible with oxidizing agents. It is sensitive to light.

참조 문헌

Charles C. McOsker.; Penny M. Fitzpatrick. Nitrofurantoin: Mechanism of action and implications for resistance development in common uropathogens. J. Antimicrob. Chemother. 1994, 33 23-30.

P. R. Hari.; T. Chandy.; C. P. Sharma. Chitosan/calcium alginate microcapsules for intestinal delivery of nitrofurantoin. Journal of Microencapsulation: Micro and Nano Carriers. 1996, 13 (3), 319-329.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H302-H334-H317

Harmful if swallowed. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.

주의 설명서: P284-P261-P280g-P342+P311a-P301+P312a-P501a

Wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves. If experiencing respiratory symptoms: Call a POISON CENTER/doctor. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

통합 관세 코드
2934.99
TSCA(독성물질규제법)"
Yes
RTECS(화학물질 독성 등록)
MU2800000

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