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It is employed as a reactant involved in 1,4-conjugate addition reactions with ethenesulfonamides to form arylethanesulfonamides, Suzuki-Miyaura reactions with dibromotrifluoromethylbenzene, cross-coupling reactions with diazoesters3 or potassium cyanate. It is involved in the synthesis of biarylketones and phthalides and synthesis of inhibitors including PDE4 inhibitors6 among others.
Robert E. London.; Scott A. Gabel. Fluorine-19 NMR Studies of Fluorobenzeneboronic Acids. 2. Kinetic Characterization of the Interaction with Subtilisin Carlsberg and Model Ligands.J. Am. Chem. Soc. 1994, 116 (6),2570-2575 .
Edward J. Farrington.; Christopher F. J. Barnard.; Elizabeth Rowsell. ;John M. Brown. Ruthenium Complex-Catalysed Heck Reactions of Areneboronic Acids; Mechanism, Synthesis and Halide Tolerance.Advanced Synthesis & Catalysis. 2005, 347 (1),185-195 .
해저드 설명서 (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
주의 설명서: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.