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80-40-0 - Ethyl p-toluenesulfonate, 98% - Ethyl tosylate - p-Toluenesulfonic acid ethyl ester - B24658 - Alfa Aesar

B24658 Ethyl p-toluenesulfonate, 98%

CAS 번호
80-40-0
동의어
Ethyl tosylate
p-Toluenesulfonic acid ethyl ester

사이즈 가격 ($) 수량 재고 여부
50g 19.30
250g 64.80
1000g 230.00
장바구니에 추가 대량 견적에 추가 항목 보기

Ethyl p-toluenesulfonate, 98%

MDL
MFCD00009100
EINECS
201-276-7

화학적 특성

화학식
C9H12O3S
화학 식량
200.26
융점
29-34°
비등점
221°
인화점
157°(314°F)
밀도
1.170
굴절률
1.5110
감도
Moisture Sensitive
용해도
Insoluble in water.

용도

Ethyl p-toluenesulfonate was used to develop an extraction method for methyl and ethyl esters of various sulfonic acids in active pharmaceutical ingredients using solid-phase micro extraction coupled to GC/MS in the selected ion monitoring mode. It was used in a study to develop a fast and accurate method for determination of residues of some common alkylating agents employed in drug synthesis by in situ derivatization-headspace-gas chromatography-mass spectrometry.

참고

Moisture sensitive. Store away from oxidizing agent.

참조 문헌

Roberto Alzaga; Robert W Ryan; Karen Taylor-Worth; Andrew M Lipczynski; Roman Szucs; Pat Sandra. A generic approach for the determination of residues of alkylating agents in active pharmaceutical ingredients by in situ derivatization-headspace-gas chromatography-mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 2007, 45 (3), 472-479.

Ivelisse Colón; Stephen M Richoll. Determination of methyl and ethyl esters of methanesulfonic, benzenesulfonic and p-toluenesulfonic acids in active pharmaceutical ingredients by solid-phase microextraction (SPME) coupled to GC/SIM-MS. Journal of Pharmaceutical and Biomedical Analysis. 2005, 39 (3-4), 477-485.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H302-H315-H319-H341-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. Suspected of causing genetic defects. May cause respiratory irritation.

주의 설명서: P201-P261-P280-P305+P351+P338-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

Merck
14,3858
바일슈타인
611213
위험 등급
6.1
포장 그룹
III
통합 관세 코드
2904.10
TSCA(독성물질규제법)"
Yes
RTECS(화학물질 독성 등록)
XT6825000

권장

최근에 본 것

화학물질

화학물질

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