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57381-39-2 - 2-Bromo-5-fluorobenzonitrile, 98+% - B24989 - Alfa Aesar

B24989 2-Bromo-5-fluorobenzonitrile, 98+%

CAS 번호
57381-39-2
동의어

사이즈 가격 ($) 수량 재고 여부
5g 46.50
25g 178.00
장바구니에 추가 대량 견적에 추가 항목 보기

2-Bromo-5-fluorobenzonitrile, 98+%

MDL
MFCD00142875
EINECS
260-711-9

화학적 특성

화학식
C7H3BrFN
화학 식량
200.01
융점
88-92°
용해도
Soluble in methanol.

용도

2-Bromo-5-fluorobenzonitrile is used in the synthesis of pyrimidine functional compounds acting as GABAAα2/α3 binding site agonists used in the treatment of anxiety disorders.

참고

Incompatible materials are oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

참조 문헌

Michael G. N. Russell; Robert W. Carling; Leslie J. Street; David J. Hallett; Simon Goodacre; Elena Mezzogori; Michael Reader; Susan M. Cook; Frances A. Bromidge; Robert Newman; Alison J. Smith; Keith A. Wafford; George R. Marshall; David S. Reynolds; Rebecca Dias; Pushpindar Ferris; Jo Stanley; Rachael Lincoln; Spencer J. Tye; Wayne F. A. Sheppard; Bindi Sohal; Andrew Pike; Maria Dominguez; John R. Atack and José L. Castro. Discovery of Imidazo[1,2-b][1,2,4]triazines as GABAA α2/3 Subtype Selective Agonists for the Treatment of Anxiety. J. Med. Chem.2006, 49, (4), 1235-1238.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H302-H312-H331-H315-H319-H335

Harmful if swallowed. Harmful in contact with skin. Toxic if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

주의 설명서: P261-P280-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

바일슈타인
8678330
위험 등급
6.1
포장 그룹
III
통합 관세 코드
2926.90
TSCA(독성물질규제법)"
No

권장

  • 43998

    Dimethyl sulfoxide, anhydrous, 99.8+%, packaged under Argon in resealable ChemSeal™ bottles

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