Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

395-01-7 - 2,2-Difluoroacetophenone, 95% - H25750 - Alfa Aesar

H25750 2,2-Difluoroacetophenone, 95%

CAS 번호
395-01-7
동의어

사이즈 가격 ($) 수량 재고 여부
250mg 58.50
1g 171.00
5g 620.00
장바구니에 추가 대량 견적에 추가 항목 보기

2,2-Difluoroacetophenone, 95%

MDL
MFCD06246879

화학적 특성

화학식
C8H6F2O
화학 식량
156.13
융점
48-50°
비등점
53-54°/12mm
굴절률
1.4955
용해도
Immiscible with water.

용도

2,2-Difluoroacetophenone acts as an intermediate in the preparation of various substances such as pharmaceuticals. Further, it is used in the one-pot synthesis of difluoromethylated arenes from aryl chlorides and bromides. In addition to this, it undergoes reduction with (-)-diisopinocampheylchloroborane chloride to get R-alcohols of purity 85% ee.

참고

Incompatible with strong oxidizing agents and strong acids.

참조 문헌

Kitamura, T.; Muta, K.; Muta, K. Hypervalent Iodine-Promoted alpha-Fluorination of Acetophenone Derivatives with a Triethylamine·HF Complex. J. Org. Chem. 2014, 79 (12), 5842-5846.

Dudzik, A.; Snoch, W.; Borowiecki, P.; Opalinska-Piskorz, J.; Witko, M.; Heider, J.; Szaleniec, M. Asymmetric reduction of ketones and beta-keto esters by (S)-1-phenylethanol dehydrogenase from denitrifying bacterium Aromatoleum aromaticum. Appl. Microbiol. Biotechnol. 2014, 99 (12), 5055-5069.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

주의 설명서: P280g-P305+P351+P338

Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

기타 참조

통합 관세 코드
2914.79
TSCA(독성물질규제법)"
No

권장

  • A11215

    Ethyl difluoroacetate, 98%
  • B24710

    DL-Penicillamine, 97+%
  • H50590

    2-(4-Bromophenyl)imidazo[1,2-a]pyridine
  • 41841

    Toluene, anhydrous, 99.8%, packaged under Argon in resealable ChemSeal™ bottles
  • H54229

    4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline, 97%

최근에 본 것

화학물질

화학물질

금속 및 재료

촉매

분석 기기 및 실험실 용품