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548-04-9 - Hypericin, 98% - 4,4',5,5',7,7'-Hexahydroxy-2,2'-dimethylnaphthodianthrone - Hypericum red - H26425 - Alfa Aesar

H26425 Hypericin, 98%

CAS 번호
548-04-9
동의어
4,4',5,5',7,7'-Hexahydroxy-2,2'-dimethylnaphthodianthrone
Hypericum red

사이즈 가격 ($) 수량 재고 여부
25mg 312.00
100mg 786.00
장바구니에 추가 대량 견적에 추가 항목 보기

Hypericin, 98%

MDL
MFCD00016683
EINECS
208-941-0

화학적 특성

화학식
C30H16O8
화학 식량
504.44
융점
ca 320° dec.
감도
Light Sensitive
용해도
Soluble in ethanol, dimethyl sulfoxide, methanol, acetone, ethylmethylketone, pyridine and sodium hydroxide. Insoluble in water.

용도

Inhibitor of protein kinase C; induces photosynthesized apoptosisHypercin acts as an antibiotic and antiviral. It is involved in the inhibition of enzyme dopamine beta-hydroxylase action. It also exhibits an anti-HIV and anticancer drug. Further, it is useful in photodynamic therapy. In addition to this, it serves as an inhibitor of protein kinase C which induces photosynthesized apoptosis.

참고

Store in a cool place. Incompatible with strong oxidizing agents.

참조 문헌

Inhibitor of protein kinase C: Biochem Biophys. Res. Commun., 165, 1207 (1989); Photochem. Photobiol., 82, 720 (2006). Antiviral and antitumour photosensitizer: Photochem. Photobiol., 54, 95 (1991); Curr. Drug Targets, 3, 55 (2002).

Kusari, S.; Sezgin, S.; Nigutova, K.; Cellarova, E.; Spiteller, M. Spatial chemo-profiling of hypericin and related phytochemicals in Hypericum species using MALDI-HRMS imaging. Anal. Bioanal. Chem. 2015, 407 (16), 4779-4791.

Vogler, A. Fluorescence spectra of complexes of hypericin with s2 metal cations. Inorg. Chem. Commun. 2015, 54, 61-62.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H302-H317

Harmful if swallowed. May cause an allergic skin reaction.

주의 설명서: P261-P280g-P301+P312a-P363-P321-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Wash contaminated clothing before reuse. Specific treatment (see label). Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

Merck
14,4863
바일슈타인
1917913
통합 관세 코드
2914.69
TSCA(독성물질규제법)"
No
RTECS(화학물질 독성 등록)
SF8472000

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