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5334-39-4 - 3-Methyl-4-nitro-1H-pyrazole, 97% - H30860 - Alfa Aesar

H30860 3-Methyl-4-nitro-1H-pyrazole, 97%

CAS 번호
5334-39-4
동의어

사이즈 가격 ($) 수량 재고 여부
5g 72.40
25g 241.00
장바구니에 추가 대량 견적에 추가 항목 보기

3-Methyl-4-nitro-1H-pyrazole, 97%

MDL
MFCD00037864

화학적 특성

화학식
C4H5N3O2
화학 식량
127.10
융점
131-134°
비등점
325°
용해도
Slightly soluble in water.

용도

3-Methyl-4-nitropyrazole is a reactant used in the preparation of aminopyrazole derivatives as potent, selective and brain penetrant Leucine-rich repeat kinase 2(LRRK2) small molecule inhibitors.

참고

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

참조 문헌

Estrada, A.A., et. al. Discovery of Highly Potent, Selective, and Brain-Penetrant Aminopyrazole Leucine-Rich Repeat Kinase 2 (LRRK2) Small Molecule Inhibitors. J. Med. Chem,2014, 57(3), 921-936.

K Chang, MR Grimmett; DD Ward; and RT Weavers. The Nitration of Brominated Pyrazoles in Aqueous Sulfuric Acid. Australian Journal of Chemistry,1979, 32 (8), 1727 - 1734.

GHS 해저드 및 주의 설명서

해저드 설명서 (EU): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

주의 설명서: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

기타 참조

통합 관세 코드
2933.19
TSCA(독성물질규제법)"
No
RTECS(화학물질 독성 등록)
UQ7435000

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화학물질

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