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4-Fluoro-3-(trifluoromethyl)aniline is used in the synthesis of trifluoromethylated poly(phenylene oxide). It is used in the preparation of 2-[3-(4-fluoro-3-trifluoromethyl-phenyl)-ureido]-2-methyl-propionic acid methyl ester by reacting with 2-isocyanato-2-methyl-propionic acid methyl ester. It is also used as a chemical intermediate in the synthesis of agrochemicals, pharmaceuticals and dyes.
Abbott, P. A.; Bonnert, R. V.; Caffrey, M. V.; Cage, P. A.; Cooke, A. J.; Donald, D. K.; Furber, M.; Hill, S.; Withnall, J. Fused mesoionic heterocycles: synthesis of [1,2,3]triazolo[1,5-a]quinoline, [1,2,3]triazolo[1,5-a]quinazoline, [1,2,3]triazolo[1,5-a]quinoxaline and [1,2,3]triazolo[5,1-c]benzotriazine derivatives. Tetrahedron 2002, 58 (16), 3185-3198.
해저드 설명서 (EU): H302-H311-H332-H315-H319
Harmful if swallowed. Toxic in contact with skin. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation.
주의 설명서: P280h-P305+P351+P338-P309-P310a-P302+P352a
Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Immediately call a POISON CENTER/doctor IF ON SKIN: Wash with plenty of water.