H32843 7-Bromoisatin, 97%
SDS
7-Bromoisatin, 97%
화학적 특성
용도
7-bromoisatin was treated with excess PhMgBr to afford tertiary alcohol 9 in 96 % yield. Isatin oxime triflates undergo a facile fragmentation which is promoted by DBU, to form anthranilonitriles after hydrolytic work-up.
참고
참조 문헌
K. C. Nicolaou,; Marco Bella,; David Y.-K. Chen,; Xianhai Huang,; Taotao Ling,; Scott A. Snyder.Total Synthesis of Diazonamide A. Angew. Chem. Int. Ed. 2002, 41(18), pg no.
James B. Campbell Jr.,; Timothy V. Davenport. Synthesis of Anthranilonitriles by Fragmentation of Isatin Oxime Triflates. Synthetic Communications: An International Journal for Rapid Communication of Synthetic Organic Chemistry. 1989, 19 (13-14), 2255-2263.
GHS 해저드 및 주의 설명서
해저드 설명서 (EU): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
주의 설명서: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.
