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Benzo[b]thiophene is used in the preparation of 2-thianapthenylphenyllithium, via metalation by n-butyllithium. It is used in organic as well as pharmaceutical industry as a component in the synthesis of raloxifene, a breast cancer therapeutic, or hydrodesulfurization reactions.
Arun M. Isloor.; Balakrishna Kalluraya.; K. Sridhar Pai. Synthesis, characterization and biological activities of some new benzo[b]thiophene derivatives. European Journal of Medicinal Chemistry. 2010, 45 (2), 825-830.
Kingo Uchida.; Yasuhide Nakayama.; Masahiro Irie. Thermally Irreversible Photochromic Systems. Reversible Photocyclization of 1,2-Bis(benzo[b]thiophen-3-yl)ethene Derivatives. Bulletin of the Chemical Society of Japan. 1990, 63 (5), 1311-1315.
Advertências de perigo (UE): H302-H313
Harmful if swallowed. May be harmful in contact with skin.
Advertências de prevenção: P273-P280f
Avoid release to the environment. Wear protective clothing.