Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

Oxazoles are five-membered heterocyclic aromatic compounds, having an oxygen atom and a nitrogen atom at the 1- and 3- positions of the ring. Oxazole is weakly basic in nature, and its conjugate acid has a pKa of 0.8. The biological activities of the oxazole moiety include anti-inflammatory, antibiotic, antiproliferative, analgesic, antifungal, hypoglycemic, anti-tuberculosis, and muscle relaxant activities. In addition to this, oxazole chemistry further involves the metalation of the oxazole ring, which has an alkyl substituent, and the reactions of these organometallic species with electrophiles. This development is useful in the synthesis of various complex oxazole ring-containing macrocyclic antibiotics.

Oxazoline is a five-membered heterocyclic organic compound similar to oxazoles except that it has one double bond in the ring. With respect to the position of the double bond, there exist three isomeric oxazolines. Oxazolines form a core structure in many biologically active compounds possessing antimycobacterial and anticancer activities. Polyoxazolines, prepared by polymerization of 2-oxazolines, have several biological applications, including coating, pigment dispersion, and many biomedical uses including drug and gene delivery. (Review: "Strategies for the Synthesis of Poly(2-oxazoline)-Based Hydrogels", Kelly, A.M., et al. Macromolecular Rapid Commun. 2012, 33(19), 1632–1647). Asymmetric catalysis with chiral 2-oxazolidine based ligands is one of the most preferred methods for chiral transformations to prepare chiral carboxylic acids, alcohols, lactones, and thiiranes. Bis-oxazolines (BOX), phosphinooxazolines (PHOX), and tris-oxazolines (TRISOX) are some of the oxazolidine-based ligands employed in asymmetric synthesis. Due to the inertness of the oxazoline ring system to various reagents like the Grignard reagent, hydrides, alkalis, mild acids, and chromium (III) oxide; it is an attractive protecting group for carboxylic acids.

  • 1,4-Bis(5-phenyloxazol-2-yl)benzene, 98+%
  • 2-(1-Naphthyl)-5-phenyloxazole, laser grade and suitable for scintillation spectrometry, 99+%
  • 2-(2,6-Dimethoxyphenyl)-4,4-dimethyl-2-oxazoline, 98+%
  • 2,4,5-Trimethyl-3-oxazoline, cis + trans, 99%
  • 2,4,5-Trimethyloxazole, 97%
  • 2,5-Bis(4-biphenylyl)oxazole, 99%
  • 2,5-Diphenyloxazole, 99%
  • 2-Aminooxazole, 97%
  • 2-Benzyl-4,4-dimethyl-2-oxazoline, 95%
  • 2-Ethyl-2-oxazoline, 99%
  • 2-Ethyl-4,4-dimethyl-2-oxazoline, 97%
  • 2-Ethyl-4,5-dimethyloxazole, 98%
  • 2-Mercapto-4,5-diphenyloxazole, 98%
  • 2-Methyl-2-oxazoline, 99%
  • 2-Methylnaphtho[2,3-d]oxazole, 98%
  • 2-Oxazolidinone, 99%
  • 2-Phenyl-5-oxazolone, 97%
  • 3-(4,4-Dimethyl-2-oxazolinyl)pyridine, 97%
  • 3,5,5-Trimethyloxazolidine-2,4-dione, 98%
  • 3-Trimethylsilyl-2-oxazolidinone
  • 4,4-Dimethyl-2-oxazoline, 98%
  • 4-[5-(4-Dimethylaminophenyl)-2-oxazolyl]benzeneboronic acid, 97%
  • 4-Ethoxymethylene-2-phenyloxazolin-5-one, 98+%
  • 4-Methyloxazole-5-methanol, 97+%
  • (4R)-(+)-4-Isopropyl-2-oxazolidinone, 98+%
  • (4S)-(-)-Isopropyl-2-oxazolidinone, 98%
  • 5-(2-Pyridyl)-1,3-oxazole, 97%
  • 5-(3-Bromophenyl)-1,3-oxazole, 97%
  • 5-Bromobenzoxazole-2-thiol, 97%
  • 5-Chlorobenzoxazole-2-thiol, 97%
  • 5-Fluorobenzoxazole-2-thiol, 97%
  • Bis(2-oxo-3-oxazolidinyl)phosphinic chloride, 97%
  • Dimethyl oxazole-4,5-dicarboxylate, 99%
  • Ethyl 2-aminooxazole-4-carboxylate, 95%
  • Ethyl 2-chlorooxazole-4-carboxylate, 95%
  • Ethyl 4-methyloxazole-5-carboxylate, 97+%
  • Ethyl oxazole-5-carboxylate, 98%
  • Oxazole-5-carboxylic acid, 98+%
  • Oxazole, 98+%
  • (R)-(+)-3-(Benzyloxycarbonyl)oxazolidine-4-carboxylic acid, 98%
  • (R)-(+)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde, 95%
  • (R)-(-)-4-(3-Indolylmethyl)-2-oxazolidinone, 98%
  • (R)-(+)-4-Benzyl-2-oxazolidinone, 99%
  • (R)-(+)-4-(Diphenylmethyl)-2-oxazolidinone, 97%
  • (R)-(-)-4-Phenyl-2-oxazolidinone, 98%
  • (S)-(-)-3-(Benzyloxycarbonyl)oxazolidine-4-carboxylic acid, 98%
  • (S)-3-(N-Fmoc-L-leucinyl)-2,2-dimethyloxazolidine-4-carboxylic acid, 95%
  • (S)-(-)-4-Benzyl-2-oxazolidinone, 99%

Químicos

Ciências da vida

Metais e materiais

Catalisadores

Equipamento analítico e de laboratório